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Class: HIV protease inhibitor PI ; Standard dose: Two 700 mg tablets twice-a-day, no food restrictions. Treatment-experienced patients should use Lexiva twice daily with Norvir 700 mg plus Norvir 100 mg, twice-a-day ; . No food restrictions may be taken with or without food ; with either dosing. Take missed dose as soon as possible, but do not double up on your next dose. Manufacturer contact: GlaxoSmithKline, lexiva , 1 888 ; 8255249 AIDS Treatment Information Service: 1 800 ; HIV0440 4480440 ; Potential side effects and toxicity: e most common side effects include: nausea, rash, diarrhea, headache, vomiting, fatigue, mood disorders, abdominal pain, and mouth numbness. Rash occurred in about 19% of patients, but severe rashes were uncommon. If you experience a rash, notify your doctor. For mild or moderate rashes, your doctor may choose to continue Lexiva, with close follow-up and monitoring. Because Lexiva is a sulfonamide, it should be used with caution in patients with allergies to sulfa drugs. Side effects and laboratory abnormalities were similar when Lexiva was taken once or twice daily, with or without Norvir. As seen with all other protease inhibitors are increased levels of cholesterol and triglycerides, except possibly unboosted Reyataz atazanavir ; and these increased levels may be associated with heart disease. Side effects and laboratory abnormalities were similar when Lexiva was taken once of twice daily, with or without Norvir. Other possible side effects are lipodystrophy body fat changes, including thinning of the face, arms and legs, with or without fat accumulation in the stomach, breasts and sometimes the upper back ; , worsening or new cases of diabetes symptoms include increased thirst and hunger, frequent urination, unexplained weight loss, fatigue, and dry itchy skin; see your doctor promptly ; and increased bleeding in hemophiliacs. Potential drug interactions: Cannot be taken with Kaletra. Like all PIs, do not take with Tambocor ecainide ; , Rythmol propafenone ; , Versed, Halcion, Hismanol, Seldane, rifampin, ergot derivatives such as Cafergot, Wigraine and Methergine, D.H.E. 45, in any form--serious interactions seen with dilation during gynecological exams ; , and the herbal supplement St. John's wort. Do not use Zocor simvastatin ; or Mevacor lovastatin lipid-lowering alternatives are Lipitor atorvastatin ; , Lescol, and Pravachol pravastatin ; , but they should be used with caution due to potential for liver toxicity. Oral solution contains alcohol, so do not use with Antabuse or Flagyl. Also avoid dihydropuridine calcium channel blockers. Protease inhibitors increase blood levels of Viagra sidenal citrate ; , so initially the Viagra dose should be 12.5 mg 1 4 of 50 mg tablet ; and increased as needed and tolerated. It's recommended that people on PIs do not exceed 25 mg of Viagra in a 48-hour period because of potential for serious reaction. Tips: Alternative dosing: Lexiva 1400 mg with Norvir 200 mg, both once daily. Studies have demonstrated that protease inhibitor-experienced patients should take Lexiva 700 mg with Norvir 100 mg, both twice daily. e once daily dosing is not recommended for treatment-experienced patients. It is important to take Lexiva exactly as your doctor instructs, and not to change dosing without discussing with your doctor. e FDA points out that the study comparing Lexiva Norvir against Kaletra in protease inhibitor experienced patients was not large enough to show that the combination was clinically equivalent to Kaletra. Due to a drug interaction between Lexiva and Kaletra, these drugs can not be used together. Lexiva is a "pro-drug" formulation of Agenerase. is means that when you take this pill, your body converts it to Agenerase. 700 mg of Lexiva is roughly equivalent to 600 mg of Agenerase. is new formulation is an improvement because it helps to make the pills smaller and easier to swallow. e new formulation also allows the drug to be given with fewer number of pills per day 4 per day ; . Approved in October 2003, Lexiva is the newest PI on the market. Pronounced "lux ee va. All hormonal drugs appearing in the formulary are considered to be safe and acceptable for monitoring and prescribing by patient's General Practitioners, once initiation and stabilisation under the care of an oncologist has occurred, this will generally be in the order of three months. * Those drugs appearing in the `Routine Use - Unrestricted' column are acceptable for use within the base line budget, but the network as part of its drug monitoring programme would like to be informed of patients or usage on at least an annual basis. * The exact indications for use under NICE guidance are detailed in the table below. * See further table below for additional details. Thalidomide use is monitored on a monthly basis by the Network, for example, ibuprofen.
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The Committee encourages cost effective prescribing and optimization of medication therapy for maximum effectiveness. This considers not only the cost of the medication, but such differences as the length of therapy and potential outcome, for instance, cafergot suppositories.
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Thyroid cancer Poster EXACERBATION OF POSTSURGICAL HYPOTHYROIDISM DURING TREATMENT OF ADVANCED DIFFERENTIATED DTC ; OR MEDULLARY MTC ; THYROID CARCINOMA WITH AMG 706 F. Pacini1, S. Sherman2, M. Schlumberger3, R. Elisei4, L. Wirth5, L. Bastholt6, J.P. Droz7, R. Martins8, M. Hofmann9, L. Locati10, M. Eschenberg11, D. Stepan11 1 University of Siena, Medicina Interna, Siena, Italy 2 University of Texas M.D. Anderson Cancer Center, Endocrine Neoplasia and Hormonal Disorders, Houston, Tex., USA 3 Institut Gustave Roussy, Service De Medecine Nucleaire, Villejuif, France; 4 University of Pisa, Endocrinology and Metabolism, Pisa, Italy; 5 Dana-Farber Cancer Institute, Head and Neck Oncology, Boston, Mass., USA; 6 Odense University Hospital, Oncology, Odense, Denmark 7 Centre Leon Berard, Lyon, France 8 Seattle Cancer Care Alliance, Medical Oncology, Seattle, Wash., USA; 9 Inselspital, Medical School Bern, Bern, Switzerland; 10 Istituto Nazionale dei Tumori, Medical Oncology, Milan, Italy; 11 Amgen Inc., Thousand Oaks, Calif, USA Purpose: To investigate the effect of AMG 706, an oral, investigational angiogenesis inhibitor, on hypothyroidism previously documented with other class molecules ; in a phase 2 safety efficacy study in patients pts ; with advanced DTC or MTC and postsurgical hypothyroidism. Methods: Multicenter, open-label, single-arm study. Eligible patients DTC n 93; MTC n 91 ; received AMG 706 125mg QD until disease progression or unacceptable toxicity. thyroid function was tested prior to the first dose and q4w while on treatment. Sera were assayed by EIA for TSH reference range 0.325.00 mU L; interassay CV 7.69% at 0.62 mU L ; and free T4 reference range 0.71.9 ng dL; interassay CV 3.94% at 1.28 ng dL ; . Results: For the DTC cohort, the baseline BL ; geometric mean TSH 95% CI ; was 0.11 mU L 0.080.15 mean fT4 was 1.57 ng dL 1.481.65 ; . TSH peaked at 0.84 mU L 0.511.38 ; p 0.0001 compared with BL ; at a mean 13.1 wks on treatment, while fT4 fell to 1.29 ng dL 1.20 1.38 ; . TSH rose 10-fold in 43% of DTC pts and 100-fold in 15%. Of 69 DTC pts with low BL TSH, 28% had a peak TSH within and 22% above the reference range. For the MTC cohort, the BL geometric mean TSH was 0.69 mU L 0.481.00 mean fT4 was 1.25 ng dL 1.181.31 ; . TSH peaked at 5.88 mU L 4.367.95 ; p 0.0001 compared with BL ; at a mean 13.5 wks on treatment, while fT4 fell to 1.06 ng dL 1.021.11 ; . TSH rose 10-fold in 48% of MTC pts and 100-fold in 9%. Of 76 MTC pts with BL TSH below or within reference range, 61% had a peak TSH above that range. Conclusion: In this study, AMG 706 therapy was associated with marked exacerbation of postsurgical hypothyroidism in DTC and MTC pts, suggesting close TSH monitoring and thyroxine dose changes to maintain appropriate TSH levels in these pts.

DOTS has been successful in improving cure rates in tuberculosis worldwide, but has remained an inefficient strategy in respect of multidrug-resistant tuberculosis MDR TB ; . The present article discusses its management in context of RNTCP and focuses specially on DOTS-plus, a strategy arising out of the constitution of Green Light Committee to effectively tackle the cases of MDR TB globally. Key words : MDR TB, RNTCP, DOTS, DOTS-plus and calan.

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May 11-12, 2006 -- Rocklin Park Hotel, Rocklin Park, CA Back to the Breast-Preserving the Breastfeeding Relationship Information: 916-780-6454 May 26, 2006 -- West Covina, CA The Impact of Birthing Practices on Breastfeeding - A Day with Linda Smith Citrus Valley Medical Center: Queen of the Valley Campus Information: 213-596-5776 breastfeedla May 26-28, 2006 -- Hilton Costa Mesa, Costa Mesa, CA Breastfeeding Now, Parenting for a Lifetime La Leche League of So California Nevada Information: 1-866-818-conf lalecheleaguescnv July 24-26, 2006 -- Mission Bay Hilton, San Diego, CA La Leche League International, 34th Physicians Seminar on Breastfeeding: Breastfeeding: Research Into Practice Information: 847-592-7561 lalecheleague August 3, 2006 -- Los Angeles, CA Critical Factors in Breastfeeding Success: A Day with "Dr. Mom" Marianne Neifert Cedars Sinai Medical Center Information: 213-596-5776 breastfeedla September 19-22, 2006 -- Niagara Falls, New York Academy of Breastfeeding Medicine's 11th Annual International Meeting: Current Controversies in Breastfeeding Medicine Information: 1800-990-4ABM bfmed August 15-19, 2007 -- San Diego, CA Town & Country Resort & Convention Center ILCA's Annual International Conference and Meeting.

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1. 2. 3. Begin chest compressions. Attempt to ventilate the patient when airway equipment is assembled. If air entry does not occur, re-adjust the airway and re-attempt ventilation. If the second ventilation does not enter the lungs, the patient is deemed to have an obstructed airway. PCP: Visualize inside the patient's mouth after every set of chest compressions and remove the obstruction if visualized. ACP: Visualize the patient's upper airway using a laryngoscope and Magill forceps or equivalent ; . Remove foreign body if visualized. 6. 7. 8. Start the medical Cardiac Arrest General Protocol performing one analysis or manual rhythm check. IV access should not be attempted until the foreign body airway obstruction is cleared. If the foreign body airway obstruction cannot be cleared: PCP: Initiate rapid transport after 2 minutes of attempting to clear the obstruction and respondingtothefirstanalysis. ACP: ifcertified ; after2failed attempts to remove the obstruction using Magill forceps. Initiate rapid transport. 9. If the obstruction is cleared, start the Cardiac Arrest General Protocol from the beginning, count any shocks analyses that have already been completed. Atings & info drug: cafergot tablet category: migraines generic name: butalbital apap caffeine manufacturer: novartis ratings are based on a maximum score of 0 correct this drug's info to send a comment back for further review, click the red flag next to the rating below ; i have had no problems with this drug at all and carbidopa.
Mild migraines--ibuprofen, Tylenol, Advil, Aleve Moderate--oral, nasal, or injection of 5HT agonists marketed as Imitrex, Relpax, Zomig, Amerge, etc. and ergot preparations marketed as wygraine, cafergot, ergomas, etc. Dopamine antagonists that are used include Reglan and Compazine. Sedation is the most common side effect of these drugs Severe migraines--If headaches occur more than 3 times per month and cause significant functional impairment, then the patient will need injectable ergot or sumatriptan. These patients are also ideal candidates for preventative treatment. These drugs must be taken daily and usually take 2-6 weeks to demonstrate benefit. This can cut down the frequency and severity of headaches by up to percent. The promising. Migrainepage discussion forum rebound from cafergot email this topic to a friend printer-friendly version of this topic archived thread - read only previous topic next topic home conferences migraine discussion protected ; original message vickig mar-07-01, cmt ; rebound from cafergot i have a question about my mother this time and levodopa. Patients with antiphospholipid syndrome will benefit from a new registry and tissue repository sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. Researchers at eight medical centers will collect clinical, demographic, and laboratory patient information that will allow comparisons among research projects. In addition to the increased risk of blood clots associated with the autoimmune disorder, thrombocytopenia and leg ulcers are frequently seen in patients with the disorder. Antiphospholipid syndrome may account for 20% of patients with deep vein thrombosis, one third of stroke patients, and 5% to 15% of patients who have recurrent miscarriages. For additional information or to be placed on a list of people to be notified when registry enrollment begins, contact Robert A. S. Roubey, MD, at apscore med.unc , or by calling 919-966-0572. x. Plan Sponsor Plan Sponsor PBM or Non Profit or PBM Common RFP Plan Design Contract Administration Carve out PBM Functions: Clinical, Rebates, etc. Drug Manufacturer and carvedilol. Oral formulations.44, 45 The available data shows that there seem to be only minor differences in the clinical profile of the oral triptans, 45, 46 although individual patients may respond differently to individual triptans, The orally dispersible ODT ; formulations of zolmitriptan and rizariptan may provide potential advantages over the usual conventional tablet formulations in terms of ease and Favourable efficacy and tolerability confirmed by large, well-designed clinical studies Efficacy not confirmed in large clinical studies, or, efficacy compromised by safety concerns Evidence indicates that the drug is not effective for migraine Aspirin and NSAIDs Clotam Rapid ; Paracetamol plus codeine Solpadeine; Migraleve ; Paracetamol monotherapy Paracetamol plus domperidone Domperamol ; Opiate analgesics Anti-emetics as monotherapy Aspirin or paracetamol plus metoclopramide Migramax; Paramax ; Barbiturates Oral ergotamine Cafergot; Migril ; Isometheptene plus paracetamol Midrid ; Triptans: Sumatriptan po, in, sc ; Imigran ; Naratriptan po ; Naramig ; Zolmitriptan po, in ; Zomig ; Rizatriptan po ; Maxalt ; Almotriptan po ; Almogran ; Eletriptan po ; Relpax. It is important for patients who are only confused at night that they are not over-sedated during the day as this may exacerbate the problem. It may be more beneficial to give sedation at 6pm or to give a small dose during the day eg. by syringe driver ; and to give additional medication at 6pm and cilostazol.
Net interest expense increased 71% in 2001 to $ 6 million, from $ 1 million in 200 this $ 5 million increase was primarily attributable to the borrowings in 2001 that funded our product line acquisitions, for example, eletriptan. Taken with: agenerase amprenavir ; , halcion triazolam ; , ergot medications cafergot, migranal, dhe 45, and others ; , propulsid cisapride ; , versed and ciprofloxacin.
Synopsis An article in the journal Gut reports that diabetes is an independent risk factor for hepatocellular carcinoma HCC ; . The study used data from the Surveillance, Epidemiology, and End-ResultsMedicare database and included 2161 patients aged 65 and older with diagnostic confirmation of HCC between 1994 and 1999. The control group included 6183 randomly selected individuals. The authors found that 43.3% of HCC patients and 19.4% of control subjects had diabetes diagnosed during the 3 years preceding the date of HCC diagnosis. After adjusting for demographic factors, the odds ratio of HCC associated with diabetes was 3.08 p 0.0001 ; . After excluding patients with hepatitis B or C virus, alcoholic liver disease or haemochromatosis, the odds ratio remained 2.87 to 3.11. Hepatitis C virus alone was associated with an odds ratio of 24.42. In the presence of diabetes, it was increased to 36.88, suggesting a synergistic interaction between the two diseases.
Mentalhealthchannel schizophrenia - description of the psychotic disorder and clarinex. Specific Activities for the Discussion Group 1. You TA's ; should select a different recorder and presenter for this discussion section 2. You should discuss in the first ten minutes the Noyes Whitney Equation and its relationship to drug absorption. A useful figure you might want to put on the board is below. These factors are clearly not equivalent between the classes of medications or within the drug classes and clindamycin and cafergot, for example, dafergot tablets. Edited by Maree Teeson, Heather Proudfoot, NDARC. Published by Commonwealth Department of Health and Ageing, 2003. Since 1st April 2001 the prescription charge for each item, preparation or type of appliance obtained on prescription has been 6.20 per item. Exemption and Remission from Prescription Charges Provided that the appropriate declaration is made upon the reverse of the prescription form, the people listed below do not have to pay the prescription charge: Men & women aged 60 and over: Children under 16 Students aged 16, 17 or 18 in full time education.; Pregnant women and women who have had a child in the previous 12 months who hold a valid exemption certificate: People suffering from the following medical conditions who hold a valid exemption certificate because they receive a War or MOD Disablement Pension. These patients only receive free prescriptions in respect of medication arising from their disablement ; . People suffering from the following medical conditions who hold a valid exemption certificate: Forms of hypoadrenalism including Addison's disease ; for which specific substitution therapy is essential. Diabetes insipidus and other forms of hypopituitarism Diabetes mellitus except where treatment is by diet alone Hypoparathyroidism Myasthenia gravis Epilepsy requiring continuous anti-convulsive therapy A continuing physical disability which prevents the patient leaving his her residence except with the help of another person. A permanent wound requiring continuous surgical dressing or an appliance; Non-exempt patients who hold a valid prescription pre-payment certificate * Non-exempt patients who are prescribed contraceptives only their contraceptive prescriptions are exempt and clobetasol.

A ACCU-CHEK BLOOD GLUCOSE METER ACCU-CHEK TEST STRIPS ACCUNEB ACIPHEX ACTIVELLA ACTOS ACULAR ADVAIR AGENERASE AGRYLIN ALINIA ALLEGRA ALLEGRA-D ALPHAGAN P ALTACE AMARYL AMBIEN ANDROGEL ARICEPT ARIMIDEX AROMASIN ARTHROTEC to be deleted, effective April 30, 2005 ; ASACOL ASCENSIA TEST STRIPS ASTELIN ATROVENT AVALIDE AVANDAMET AVANDIA AVAPRO AVONEX AZMACORT B BD TEST STRIPS BETASERON BETIMOL to be deleted, effective April 30, 2005 ; BEXTRA to be deleted, effective April 30, 2005 ; BRAVELLE C CAFERGOT CANASA CARAC CARDIZEM LA CASODEX CEENU CELEBREX CELLCEPT CENESTIN CERUMENEX to be deleted, effective April 30, 2005 ; CETROTIDE CIPRODEX CLIMARA CLIMARA PRO COMBIVENT COMBIVIR COMTAN CONCERTA CONDYLOX GEL COPAXONE COPEGUS COREG CORTEF CORTIFOAM COZAAR CREON CRIXIVAN CUPRIMINE CYTOXAN D DANTRIUM to be deleted, effective April 30, 2005 ; DAPSONE DEPAKOTE DEPAKOTE ER DEPAKOTE SPRINKLE DETROL DILANTIN DIPENTUM DOSTINEX DOVONEX DUONEB DURAGESIC E EFFEXOR EFFEXOR XR EFUDEX CREAM ELMIRON to be deleted, effective April 30, 2005 ; EMCYT ENTOCORT EC EPINEPHRINE INJECTION EPIVIR EPIVIR-HBV EPZICOM ERGAMISOL ESCLIM to be deleted, effective April 30, 2005 ; ESTRADERM ESTRATEST ESTRATEST HS ETHMOZINE EVISTA EVOXAC EXELON F FARESTON FEMARA FINACEA FLOMAX FLONASE FLOVENT FLOVENT ROTADISK FLOXIN OTIC FLUOROPLEX to be deleted, effective April 30, 2005 ; FORADIL AEROLIZER FORTOVASE FOSAMAX FREESTYLE TEST STRIPS FULVICIN P G FULVICIN U F G GLEEVEC GLUCAGON GLUCO-DEX TEST STRIPS GLUCOSTIX TEST STRIPS H HELIDAC HEPSERA HEXALEN HIVID HYZAAR I IMITREX, all forms INFERGEN to be deleted, effective April 30, 2005 ; INNOPRAN XL INTAL INHALER INTRON A INVIRASE K KALETRA, capsule and solution KEPPRA KYTRIL L LAMICTAL LAMISIL LESCOL LESCOL XL LEUKERAN LEVAQUIN LEVBID LEVSINEX to be deleted, effective April 30, 2005 ; LEXAPRO LEXIVA LIDODERM LIPITOR LOPROX TOPICAL CREAM AND GEL LOTEMAX LOVENOX LUMIGAN LYSODREN M MALARONE to be deleted, effective April 30, 2005 ; MAXALT MEPHYTON METADATE CD METADATE ER METHERGINE METROGEL VAGINAL MIACALCIN MIGRANAL MIRAPEX MYLERAN MYLOCEL N NAMENDA NARDIL NASONEX NEUPOGEN NIASPAN NILANDRON NORITATE NORVASC NORVIR NOVOLIN NOVOLOG NOVOLOG MIX 70 30 NULEV to be deleted, effective April 30, 2005 ; NUTROPIN NUTROPIN AQ NUTROPIN DEPOT NUVARING O ONE TOUCH GLUCOMETER ONE TOUCH TEST STRIP ORTHO EVRA ORTHO TRI-CYCLEN LO OVIDE OXSORALEN ULTRA OXYCONTIN OXYTROL P PARNATE PEGASYS PEG-INTRON PHOSLO PLAN B PLAVIX PRANDIN PRAVACHOL PRECOSE PRED MILD PREDNISONE 1MG PREMARIN PREMARIN CREAM PREMPHASE PREMPRO PREVEN PROCTOFOAM HC PROGRAF PROSCAR PROTOPIC to be deleted, effective April 30, 2005 ; PRO VIGIL PULMICORT RESPULES PULMICORT TURBUHALER PULMOZYME Q QUIXIN QVAR R RAPAMUNE REBETRON REBIF RELPAX to be deleted, effective April 30, 2005; alternative is MAXALT ; * REMINYL RENAGEL REQUIP RESCRIPTOR RESTASIS RESTORIL--7.5MG DOSE ONLY RETIN-A MICRO RETROVIR RHINOCORT AQUA RIDAURA RISPERDAL S SAIZEN SEREVENT SEREVENT DISKUS SEROQUEL SINGULAIR SONATA SPIRIVA STALEVO. Bring all your medications when you see your doctor. Or make a list of their names, how much you take, and how often you take them. This will give your doctor a complete picture of the medications you are taking. Then he or she can decide the best approach for your situation. You should not take the following medications if you are taking SUSTIVA. Taking these medications with SUSTIVA could create the potential for serious and or life-threatening side effects: CISAPRIDE * MIDAZOLAM TRIAZOLAM e.g, HALCION ; ERGOT MEDICATIONS e.g, CAFERGOT ; VORICONAZOLE VFEND.

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This patient had established toxicity on presentation coma, hypotension and severe metabolic acidosis ; , and so it is difficult to predict, based on this case, whether earlier intervention with agents such as nac would have an impact on outcome.

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Whereas the current licensed dose is three capsules twice daily irrespective of weight. No significant adverse events were seen. The results of this pilot study warrant further investigation in the form of a randomised controlled clinical trial using standard HAART as a comparator. Arribas et al2 presented data on 42 patients in a 24-week, randomised open label pilot trial, on simplification to single agent Kaletra in an induction-maintenance strategy. Patients were eligible if they were taking HAART consisting of Kaletra and two nucleoside reverse transcriptase inhibitors for at least one month and had had an undetectable VL 50cpm ; for at least six months prior to enrolment. Patients were randomised on a 1: basis either to continue with their present three drug regimen or reduce to single agent Kaletra. At week 24, of those patients still on therapy on treatment analysis ; , 100 per cent in the triple drug arm remained undetectable with a VL 50cpm versus 95 per cent of patients in the simplification arm. In the ITT analysis non completer failure ; , 81 per cent in the simplification arm remained undetectable versus 100 per cent in the triple drug arm. The three failures, which were all in the simplification arm, each had genotypic resistance testing performed, none of which demonstrated the development of resistance mutations in the protease genome to Kaletra. This study demonstrated that a large proportion of patients simplified to single agent Kaletra remain with an undetectable VL after 24 weeks of therapy and preliminary data show that failures are not associated with the development of resistance mutations, which means that future treatment options are not jeopardised and calan.

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