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Ents. J Psychosoc Nurs Ment Health Serv 1994; 32: 9-13. Haight BK. The therapeutic role of a structured life review process in homebound elderly subjects. J Gerontol 1988; 43: 40-4. McDougall GJ, Blixen CE, Suen L. The process and outcome of life review psychotherapy with depressed homebound older adults. Nurs Res 1997; 46: 277-83. Banerjee S, Shamash K, Macdonald AJ, Mann AH. Randomised controlled trial of effect of intervention by psychogeriatric team on depression in frail elderly people at home. BMJ 1996; 313: 1058-61. Wells KB, Rogers WH, Davis LM, Kahn K, Nordquist G, Keeler E, et al. Quality of care for hospitalized depressed elderly patients before and after implementation of the Medicare Prospective Payment System. J Psychiatr 1993; 150: 1799-805. Flaherty JH, McBride M, Marzouk S, Miller DK, Chien N, Hanchett M, et al. Decreasing hospitalization rates for older home care patients with symptoms of depression. J Geriatr Soc 1998; 46: 31-8. Bultema JK, Mailliard L, Getzfrid MK, Lerner RD, Colone M. Geriatric patients with depression. Improving outcomes using a multidisciplinary clinical path model. J Nurs Adm 1996; 26: 31-8. Home, length of hospital stay, and cost. A community-based study. Stroke 1995; 26: 1178-82. Patel M, Potter J, Perez I, Kalra L. The process of rehabilitation and discharge planning in stroke: a controlled comparison between stroke units. Stroke 1998; 29: 2484-7. Falconer JA, Naughton BJ, Strasser DC, Sinacore JM. Stroke inpatient rehabilitation: a comparison across age groups. J Geriatr Soc 1994; 42: 39-44. Stineman MG, Ross RN, Hamilton BB, Maislin G, Bates B, Granger CV, et al. Inpatient rehabilitation after stroke: a comparison of lengths of stay and outcomes in the Veterans Affairs and non-Veterans Affairs health care system. Med Care 2001; 39: 123-37. Werner RA, Kessler S. Effectiveness of an intensive outpatient rehabilitation program for postacute stroke patients. J Phys Med Rehabil 1996; 75: 114-20, Hui E, Lum CM, Woo J, Or KH, Kay RLC. Outcomes of Elderly Stroke Patients: Day Hospital Versus Conventional Medical Management. Stroke 1995; 26: 1616-19. Young J, Forster A. Day hospital and home physiotherapy for stroke patients: a comparative cost-effectiveness study. J R Coll Physicians Lond 1993; 27: 252-8. Anderson C, Rubenach S, Mhurchu CN, Clark M, Spencer C, Winsor A. Home or hospital for stroke rehabilitation? results of a randomized controlled trial : I: health outcomes at 6 months. Stroke 2000; 31: 1024-31. Anderson C, Mhurchu CN, Rubenach S, Clark M, Spencer C, Winsor A. Home and tegaserod, for instance, side affects.

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Jonathan Belsey This is a well conducted quantitative systematic review that meets all the quality standards expected of this type of publication. It has been written up clearly and concisely and, assuming that the data presented in the accompanying spreadsheets are published as tables, there is sufficient data available for the analysis to be replicated, if required. The conclusions drawn are consistent with the data presented and will be of clear value to those responsible for initiating home treatment of genital warts. There are two specific issues that I would like to see covered more fully in the final published version: 1. As imiquimod is considerably more expensive than the other currently licensed home treatment - podophyllotoxin - it will be important for prescribers to try to quantify the degree of additional benefit associated with imiquimod. It would therefore be useful to have a paragraph in the introduction giving some idea as to the efficacy tolerability of podophyllotoxin or, if such studies do not exist, a statement to that effect. 2. In the statistical analysis a fixed effects model is used. This may well be justified but, as heterogeneity testing methods have now been somewhat discredited, it is difficult to be sure. As the number of studies involved was small, it may well be worthwhile reporting whether the wider confidence intervals one would expect with the use of a random effects model would have had any impact on the conclusions of the analysis. Level of interest A paper whose findings are important to those with closely related research interests Advice on publication Accept after revision, which I do not need to see Quality of written English Acceptable Competing interests Have you in the past five years received reimbursements, fees, funding, or salary from an organisation that may in any way gain or lose financially from the publication of this paper? If so, please specify. I have received payments from Hayward Medical Communications in the past for the. 4.4.2 ANTIPLATELET DRUGS TIER 1 L Dipyridamole + Persantine + ; Sulfinpyrazone + Anturane + ; Cilostazol + Pletal + ; Ticlopidine HCl + Ticlkd + ; TIER 2 Plavix Clopidogrel Bisulfate. Were taking additional therapy with aspirin, -blockers, or lipid-lowering drugs at the onset of the trial. The mechanism of this benefit remains speculative.

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